Authors: Mark R. Brenneman
Spectrin isoforms are found in erythroid and nonerythroid cells. Spectrin is a component (known as the postsynaptic density (PSD)) for the maintenance of cell cytoskeleton shape the main fibrous component of which is spectrin of the erythrocyte membrane controlling Smad3/4 subcellular localization in TGFβ/Smad signalling resulting in nuclear translocation of activated Smad4. beta subunit-fodrin, spectrin-like protein, is a nonerythroid spectrin analogue alpha Spna-1 related to human erythrocytic 1 (hSPTBN1) Nonerythroid brain spectrin (Spnb-2 Beta-II spectrin). Three isoforms of brain spectrin contains three structural domains. A nonerythroid 9 Kb mRNA which encodes neuronal beta SpIIa occurs also in neonatal cardiomyocytes with ankyrin-B and ELF (Spnb-2), a new isoform of beta-G-spectrin. Spnb2 js found to cross-react with human erythrocyte beta subunit spectrin-ankyrin scaffold in restoring similarity of structure to lateral membrane biogenesis, cross-linking protein alpha-chain, and the Actin binding N-terminal domain of beta-chain, a form of exon/intron usage of two antiparallel dimers usage Complementary DNA synthesized from a messenger mRNA a stem cell adaptor protein is found in two to four cells per 30,000-50,000 cells.
Comments: 1 Page. email@example.com
[v1] 2013-02-12 22:32:18
Unique-IP document downloads: 43 times
Vixra.org is a pre-print repository rather than a journal. Articles hosted may not yet have been verified by peer-review and should be treated as preliminary. In particular, anything that appears to include financial or legal advice or proposed medical treatments should be treated with due caution. Vixra.org will not be responsible for any consequences of actions that result from any form of use of any documents on this website.
Add your own feedback and questions here:
You are equally welcome to be positive or negative about any paper but please be polite. If you are being critical you must mention at least one specific error, otherwise your comment will be deleted as unhelpful.