Chemistry

   

Comment on "Are Mechanistic and Statistical QSAR Approaches Really Different? MLR Studies on 158 Cycloalkyl-Pyranones [Bhhatarai et al., Mol. Inf. 2010, 29, 511-522]"

Authors: Sierra Rayne

In their study, Bhhatarai et al. [Mol. Inf. 2010, 29, 511-522] develop quantitative structure-activity relationships (QSARs) for the inhibition of HIV protease by 158 so-called 4-OH cycloalkyl-pyranones. A number of compounds termed 4-OH cycloalkyl-pyranones in this work do not appear to be cycloalkyl-pyranones.

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[v1] 2013-03-09 22:03:28

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