Biochemistry

1610 Submissions

[2] viXra:1610.0321 [pdf] submitted on 2016-10-27 06:22:29

Cystic Fibrosis: Computing the World's First Cure for a Genetic Disease

Authors: James Bonnar
Comments: 80 Pages.

Cystic fibrosis (CF) affects millions of people worldwide. In this book we discuss both the technical and non-technical reasons science has been unable to find cures for inherited diseases such as CF, despite the exponential increase in knowledge of disease mechanisms we currently witness. New directions in scientific research and protocols are suggested that may help bring about actual cures for genetic diseases through medicinal gene therapy. A new computational approach, called the omega algorithm, is developed, implemented and applied to find compounds that could potentially correct the delta F508 mutation responsible for cystic fibrosis. Links to downloadable files, including an extensive chemical reaction database, are given in an appendix to assist the reader with their own further studies. All computer code in the book is written in the Mathematica language.
Category: Biochemistry

[1] viXra:1610.0131 [pdf] submitted on 2016-10-12 23:59:46

Evaluation of Biochemical Marker Glutathione and DNA Fingerprinting of Biofield Energy Treated Oryza Sativa

Authors: Mahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi, Gopal Nayak
Comments: 6 Pages.

Food production needs to increase to satisfy the demand due to increasing human population worldwide. To minimize this food crisis, an increase in the rice production is necessary in many countries. The current study was undertaken to evaluate the impact of Mr. Trivedi’s biofield energy treatment on rice (Oryza sativa) for its growth-germination of seedling, glutathione (GSH) content in seedling and mature plants, indole acetic acid (IAA) content in shoots and roots and DNA polymorphism by random amplified polymorphic-DNA (RAPD). The sample of O. sativa cv, 644 was divided into two groups. One group was remained as untreated and coded as control, while the other group was subjected to Mr. Trivedi for biofield energy treatment and denoted as treated sample. The growth-germination of O. sativa seedling data exhibited that the biofield treated seeds was germinated faster on day 3 as compared to control (on day 5). The shoot and root length of seedling was slightly increased in the treated seeds of 10 days old with respect to untreated seeds. Moreover, the plant antioxidant i.e. GSH content in seedling and in mature plants was significantly increased by 639.26% and 56.24%, respectively as compared to untreated sample. Additionally, the plant growth regulatory constituent i.e. IAA level in root and shoot was significantly (p<0.05) increased by 106.90% and 20.35%, respectively with respect to control. Besides, the DNA fingerprinting data using RAPD, revealed that the treated sample showed an average range of 5 to 46% of DNA polymorphism as compared to control. The overall results envisaged that the biofield energy treatment on rice seeds showed a significant improvement in germination, growth of roots and shoots, GSH and IAA content in the treated sample. In conclusion, the treatment of biofield energy on rice seeds could be used as an alternative way to increase the production of rice.
Category: Biochemistry