Physics of Biology

2202 Submissions

[2] viXra:2202.0033 [pdf] submitted on 2022-02-06 19:43:22

Integration of Bioinspired Artificial Channels for the Concept Design of an Artificial Kidney Device

Authors: A. Alayoud
Comments: 23 Pages.

Recently, there has been a great interest in the possible applications of synthetic transporters that mimic the structures and functions of natural ion channels for liquid separations, water purification, and biosensing. Here we propose, for the first time, the use of selective polymer membranes incorporated by synthetic artificial carriers combined with existing dialysis technologies to create a synthetic nephron. Consistent with renal physiology, the proposed system has 3 distinct sections, replicating the glomerular filtration and tubular functions (secretion and reabsorption) and may represent a breakthrough in renal replacement therapy based on the functioning of native kidneys. Thus, this design can be used to manufacture a dialysis machine, with technical features capable of allowing dialysis treatment without ultrapure water or concentrate.
Category: Physics of Biology

[1] viXra:2202.0015 [pdf] submitted on 2022-02-03 20:10:53

The Axon: Restructuring Waves and Electrical Currents

Authors: Lev I. Verkhovsky
Comments: 7 Pages.

An article “The Brain, Reimagined,” by Douglas Fox (Sci. Am.,v.27, No 3, Fall 2018) concerns work by physicists T. Heimburg and A.D. Jackson, who argue that signals in neurons are conveyed by mechanical waves of expansion and contraction of the cell membrane rather than by electrical spikes, or action potentials, as described by the Huxley-Hodgkin theory. But the chief provisions of this theory are firmly established. Hypothesis on the honeycomb structure of the lipid biomembrane by Dr. R.-H.N. Mikelsaar makes it possible to remove the contradictions between these two concepts.
Category: Physics of Biology